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In clinical trials, participants lost between 5% and 15% of body weight, especially when combined with semaglutide

Drug treatment during food restriction Adult wild-type C57BL/6 male mice were subjected to the same 60% food restriction protocol described earlier, except that they received twice a day (at 9:00 am and 6:00 pm

Corsini EM, Mitchell KG, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Swisher SG , Roth JA, Hofstetter WL, Vaporciyan AA, Morris VK, Antonoff MB

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[PubMed] [Google Scholar] 136.Seelig G.F., Meister A